Marktanalyse - Ischemia Reperfusion Injury - Pipeline Review, H1 2017

Global Markets Direct
02.2017
148 Seiten

 
Typ:
Marktanalyse
Verfüg­barkeit:
verfügbar
Regionen/­Länder:
  • Europa
  • Asien / Pazifik
  • Mittlerer Osten / Afrika
  • Nordamerika / USA
  • Australien
  • Mittel- / Südamerika
Sprache:
Englisch

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Ischemia Reperfusion Injury - Pipeline Review, H1 2017


Summary


Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Ischemia Reperfusion Injury — Pipeline Review, H1 2017, provides an overview of the Ischemia Reperfusion Injury (Cardiovascular) pipeline landscape.

Ischemic reperfusion injury is the tissue damage that happens when blood supply returns to the tissue after a period of lack of oxygen. The absence of oxygen and nutrients creates a condition in which the restoration of circulation results in inflammation and oxidative damage through the induction of oxidative. Symptoms include headache, bradycardia, seizures and hypertension. Risk factors include hypertension, hyperlipidemia, diabetes, insulin resistance, heart failure, altered coronary circulation, and aging.

Report Highlights

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Ischemia Reperfusion Injury — Pipeline Review, H1 2017, provides comprehensive information on the therapeutics under development for Ischemia Reperfusion Injury (Cardiovascular), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Ischemia Reperfusion Injury (Cardiovascular) pipeline guide also reviews of key players involved in therapeutic development for Ischemia Reperfusion Injury and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase II, Phase I, Preclinical and Discovery stages are 4, 4, 26 and 4 respectively. Similarly, the Universities portfolio in Preclinical and Discovery stages comprises 22 and 4 molecules, respectively.

Ischemia Reperfusion Injury (Cardiovascular) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Direct’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.


Scope

- The pipeline guide provides a snapshot of the global therapeutic landscape of Ischemia Reperfusion Injury (Cardiovascular).
- The pipeline guide reviews pipeline therapeutics for Ischemia Reperfusion Injury (Cardiovascular) by companies and universities/research institutes based on information derived from company and industry-specific sources.
- The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
- The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
- The pipeline guide reviews key companies involved in Ischemia Reperfusion Injury (Cardiovascular) therapeutics and enlists all their major and minor projects.
- The pipeline guide evaluates Ischemia Reperfusion Injury (Cardiovascular) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
- The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
- The pipeline guide reviews latest news related to pipeline therapeutics for Ischemia Reperfusion Injury (Cardiovascular)


Reasons to buy

- Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
- Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
- Find and recognize significant and varied types of therapeutics under development for Ischemia Reperfusion Injury (Cardiovascular).
- Classify potential new clients or partners in the target demographic.
- Develop tactical initiatives by understanding the focus areas of leading companies.
- Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
- Formulate corrective measures for pipeline projects by understanding Ischemia Reperfusion Injury (Cardiovascular) pipeline depth and focus of Indication therapeutics.
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
- Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.
Table of Contents

Table of Contents 2

List of Tables 4

List of Figures 5

Introduction 6

Global Markets Direct Report Coverage 6

Ischemia Reperfusion Injury - Overview 7

Ischemia Reperfusion Injury - Therapeutics Development 8

Pipeline Overview 8

Pipeline by Companies 9

Pipeline by Universities/Institutes 12

Products under Development by Companies 15

Products under Development by Universities/Institutes 17

Ischemia Reperfusion Injury - Companies Involved in Therapeutics Development 20

Amyndas Pharmaceuticals LLC 20

Angion Biomedica Corp 20

Biomedica Management Corp (Inactive) 21

Bolder Biotechnology Inc 21

Corline Biomedical AB 22

Curatis Pharma GmbH 22

Erimos Pharmaceuticals LLC 23

Hope Pharmaceuticals Inc 23

Ischemix Inc 24

Kowa Company Ltd 24

NovelMed Therapeutics Inc 25

Omeros Corp 25

Opsona Therapeutics Ltd 26

Orexo AB 26

Pharming Group NV 27

Prolong Pharmaceuticals LLC 27

Proteo Inc 28

Prothix BV 28

Recordati SpA 29

SBI Pharmaceuticals Co Ltd 29

Ischemia Reperfusion Injury - Therapeutics Assessment 30

Assessment by Target 30

Assessment by Mechanism of Action 33

Assessment by Route of Administration 36

Assessment by Molecule Type 38

Ischemia Reperfusion Injury - Drug Profiles 40

AM/AMBP-1 - Drug Profile 40

aminolevulinic acid hydrochloride - Drug Profile 41

ANV-6L15 - Drug Profile 42

AP-39 - Drug Profile 43

APP-103 - Drug Profile 44

BB-3 - Drug Profile 45

BBT-059 - Drug Profile 49

BMC-011 - Drug Profile 50

C1 esterase inhibitor (recombinant) - Drug Profile 51

CMX-2043 - Drug Profile 58

CRX-526 - Drug Profile 60

Curaglutide - Drug Profile 61

Des-Asp Angiotensin 1 - Drug Profile 62

EP-80317 - Drug Profile 63

FDY-5301 - Drug Profile 64

hemin (human) - Drug Profile 65

KN-93 - Drug Profile 66

MG-53 - Drug Profile 68

mirococept - Drug Profile 70

Monoclonal Antibodies to Inhibit MMP-8 for Renal Ischemia and Shock - Drug Profile 71

Monoclonal Antibody to Inhibit CD47 for Cardiovascular Disease, Kidney Transplantation and Oncology - Drug Profile 72

Monoclonal Antibody to Inhibit Complement C3 and Complement C5 for Ischemia Reperfusion Injury - Drug Profile 74

Monoclonal Antibody to Inhibit IL-16 for Renal Ischemia Reperfusion Injury - Drug Profile 75

Neutrolide - Drug Profile 76

NK-104 NP - Drug Profile 78

NP-202 - Drug Profile 79

Oligonucleotide for Oncology and Cardiovascular Diseases - Drug Profile 80

OMS-721 - Drug Profile 81

OPN-305 - Drug Profile 88

PEG-HCC - Drug Profile 91

Peptides to Modulate SRC Family Kinase for Ischemia Reperfusion Injury - Drug Profile 92

PRO-02 - Drug Profile 93

R-190 - Drug Profile 94

Recombinant Protein for Acute Kidney Injury, Acute Radiation Syndrome, Inflammatory Bowel Disease, Ischemic Organ Injury, and Sepsis - Drug Profile 96

Recombinant Protein for Age Related Macular Degeneration - Drug Profile 97

Recombinant Protein to Agonize Robo1 for Ischemia Reperfusion Injury and Thrombosis - Drug Profile 98

Recombinant Protein to Antagonize EPHA4 for Amyotrophic Lateral Sclerosis, Acute Spinal Cord Injury, Sepsis and Ischemia Reperfusion Injury - Drug Profile 99

Recombinant Proteins for Ischemia Reperfusion Injury and Hypoxia - Drug Profile 100

Recombinant Proteins to Agonize PTCH1 for Ischemia Reperfusion Injury - Drug Profile 101

Recombinat Protein to Antagonize Interleukin-1 Receptor for Cardiomyopathy and Ischemia Reperfusion Injury - Drug Profile 102

Renaparin - Drug Profile 103

Sanguinate - Drug Profile 104

Small Molecule to Agonize Adenosine Receptor for Neurodegenerative Diseases and Ischemia Reperfusion Injury - Drug Profile 106

Small Molecule to Inhibit Arginase-1 and Arginase-2 for Myocardial Ischemia and Ischemia Reperfusion Injury - Drug Profile 107

Small Molecule to Inhibit HSP90 for Ischemia Reperfusion Injury - Drug Profile 108

Small Molecules for Ischemia Reperfusion Injury - Drug Profile 109

Small Molecules for Ischemia Reperfusion Injury - Drug Profile 110

Small Molecules for Ischemia Reperfusion Injury - Drug Profile 111

Small Molecules for Ischemia Reperfusion Injury and Inflammation - Drug Profile 112

Small Molecules for Myocardial Ischemia Reperfusion Injury - Drug Profile 113

Small Molecules to Activate Protein Kinase B for Ischemia Reperfusion Injury - Drug Profile 114

Small Molecules to Activate SGK-1 for Ischemic Reperfusion Injury - Drug Profile 115

Small Molecules to Inhibit PDE5 for Cardiovascular Disease - Drug Profile 116

sodium nitrite - Drug Profile 117

Synthetic Peptides for Ischemia Reperfusion Injury - Drug Profile 118

Synthetic Peptides for Oncology, Immunology and Cardiovascular Disorders - Drug Profile 119

terameprocol - Drug Profile 120

tiprelestat - Drug Profile 121

TMS-007 - Drug Profile 125

UCF-101 - Drug Profile 126

UWA-TAT - Drug Profile 127

Vanadis-03 - Drug Profile 128

VCP-746 - Drug Profile 129

YQ-23 - Drug Profile 130

Ischemia Reperfusion Injury - Dormant Projects 131

Ischemia Reperfusion Injury - Discontinued Products 134

Ischemia Reperfusion Injury - Product Development Milestones 135

Featured News & Press Releases 135

Appendix 142

Methodology 142

Coverage 142

Secondary Research 142

Primary Research 142

Expert Panel Validation 142

Contact Us 142

Disclaimer 143





List of Tables

Number of Products under Development for Ischemia Reperfusion Injury, H1 2017

Number of Products under Development by Companies, H1 2017

Number of Products under Development by Companies, H1 2017 (Contd..1), H1 2017

Number of Products under Development by Universities/Institutes, H1 2017

Number of Products under Development by Universities/Institutes, H1 2017 (Contd..1), H1 2017

Products under Development by Companies, H1 2017

Products under Development by Companies, H1 2017 (Contd..1), H1 2017

Products under Development by Universities/Institutes, H1 2017

Products under Development by Universities/Institutes, H1 2017 (Contd..1), H1 2017

Ischemia Reperfusion Injury - Pipeline by Amyndas Pharmaceuticals LLC, H1 2017

Ischemia Reperfusion Injury - Pipeline by Angion Biomedica Corp, H1 2017

Ischemia Reperfusion Injury - Pipeline by Biomedica Management Corp (Inactive), H1 2017

Ischemia Reperfusion Injury - Pipeline by Bolder Biotechnology Inc, H1 2017

Ischemia Reperfusion Injury - Pipeline by Corline Biomedical AB, H1 2017

Ischemia Reperfusion Injury - Pipeline by Curatis Pharma GmbH, H1 2017

Ischemia Reperfusion Injury - Pipeline by Erimos Pharmaceuticals LLC, H1 2017

Ischemia Reperfusion Injury - Pipeline by Hope Pharmaceuticals Inc, H1 2017

Ischemia Reperfusion Injury - Pipeline by Ischemix Inc, H1 2017

Ischemia Reperfusion Injury - Pipeline by Kowa Company Ltd, H1 2017

Ischemia Reperfusion Injury - Pipeline by NovelMed Therapeutics Inc, H1 2017

Ischemia Reperfusion Injury - Pipeline by Omeros Corp, H1 2017

Ischemia Reperfusion Injury - Pipeline by Opsona Therapeutics Ltd, H1 2017

Ischemia Reperfusion Injury - Pipeline by Orexo AB, H1 2017

Ischemia Reperfusion Injury - Pipeline by Pharming Group NV, H1 2017

Ischemia Reperfusion Injury - Pipeline by Prolong Pharmaceuticals LLC, H1 2017

Ischemia Reperfusion Injury - Pipeline by Proteo Inc, H1 2017

Ischemia Reperfusion Injury - Pipeline by Prothix BV, H1 2017

Ischemia Reperfusion Injury - Pipeline by Recordati SpA, H1 2017

Ischemia Reperfusion Injury - Pipeline by SBI Pharmaceuticals Co Ltd, H1 2017

Number of Products by Stage and Target, H1 2017

Number of Products by Stage and Target, H1 2017 (Contd..1), H1 2017

Number of Products by Stage and Mechanism of Action, H1 2017

Number of Products by Stage and Mechanism of Action, H1 2017 (Contd..1), H1 2017

Number of Products by Stage and Route of Administration, H1 2017

Number of Products by Stage and Molecule Type, H1 2017

Ischemia Reperfusion Injury - Dormant Projects, H1 2017

Ischemia Reperfusion Injury - Dormant Projects, H1 2017 (Contd..1), H1 2017

Ischemia Reperfusion Injury - Dormant Projects, H1 2017 (Contd..2), H1 2017

Ischemia Reperfusion Injury - Discontinued Products, H1 2017





List of Figures

Number of Products under Development for Ischemia Reperfusion Injury, H1 2017

Number of Products under Development by Companies, H1 2017

Number of Products under Development by Universities/Institutes, H1 2017

Number of Products by Top 10 Targets, H1 2017

Number of Products by Stage and Top 10 Targets, H1 2017

Number of Products by Top 10 Mechanism of Actions, H1 2017

Number of Products by Stage and Top 10 Mechanism of Actions, H1 2017

Number of Products by Routes of Administration, H1 2017

Number of Products by Stage and Routes of Administration, H1 2017

Number of Products by Molecule Types, H1 2017

Number of Products by Stage and Molecule Types, H1 2017

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