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Studie - Innovations in Diabetes Management with Food and Drinks: Key ingredients, NPD, emerging business models and leading innovators

Business Insights

Business Insights

11 / 2010
171 Seiten
Typ: Studie
Sprache: Englisch
Regionen: Europa, Asien / Pazifik, Mittlerer Osten / Afrika, Nordamerika / USA, Australien, Mittel- / Südamerika
Verfügbarkeit: verfügbar

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Diabetes affects over 285 million people around the world and this it forecast to increase to 438 million by 2030. Diabetes is strongly associated with obesity; the term 'diabesity” is increasingly being used by researchers in this field. Leading diabetes associations encourage the adoption of a 'healthy” diet, low in saturated fats and carbohydrates and rich in fruit and vegetables to improve blood sugar control, reduce weight gain, and minimize long-term complications. In addition, low glycemic index (GI) diets may be useful in weight control, and help reduce insulin levels and insulin resistance Food, ingredient and drinks manufacturers have adopt a variety of strategies to improve the nutritious content of food and beverages in response to dietary guidelines and the rising diabetes epidemic. Whilst the first phase has targeted a reduction in salt, fat and sugar (often through the incorporation of artificial low calorie sweeteners); companies are now turning to additional nutrients and functional ingredients to promote health benefits. These include the incorporation of vitamins and mineral, modified fibers and prebiotics as well as a diverse range of phytonutrients.

This report reviews the business strategies of leading companies in the development of novel products that can improve blood glucose control and weight management. It discusses the changes in regulation and reviews health claims associated with functional ingredients and supplements. It highlights the important role of personalized nutrition in the treatment and prevention of diabetes.

Scope of this research

* Identifies ingredient and supplements that may be beneficial in the treatment and prevention of diabetes and reviews the evidence to support claims.
* Review market drivers regarding the uptake of 'healthier” foods in blood glucose management and the personalization of nutrition.
* Assess the impact diabetes in the emerging economies and discuss the ways in which emerging consumer may be targeted.
* Review regulations to gain insight into the effect of these regulations on the industry in the near future.
* Identify points of convergence of the pharma, food and drinks markets in the prevention of diabetes and the emergence of healthcare nutrition.

Research and analysis highlights

The food market is changing: Over the past decade, consumers have become more concerned for their health and wellbeing. The roll of the food and drinks industry is changing and shifting towards a more benefit driven and preventative approach.

Regulations in this competitive marketplace are evolving to encourage innovation whilst protect consumer safety. This is particularly pertinent given the gap between the regulation of supplements and that of functional ingredients.

Rising cost of product development: Companies are increasingly using a science driven approach to development new products which target diabetes. This cost time and resources and requires technical expertise. Through strategic alliances and acquisitions companies have begun to expand their product portfolios and technological capabilities.

Key reasons to purchase this research

* Which companies and innovative products are available to diabetic consumers and what strategies and ingredients are companies adopting?
* In what ways are companies utilising technologies to identify and validate new products which help regulate blood glucose, and to support claims?
* What new market opportunities exist for food and drinks manufacturers to strengthen the line between food and pharma in the prevention of diabetes?
* What the are key drivers for the emergence of healthcare nutrition and the development of personalized nutrition for diabetics, now and in the future?
* What is the regulatory status of ingredients and supplements which target diabetes and how will changes in these regulations affect the industry?
Table of Contents

About the author 2

Disclaimer 2

Executive summary 11

Introduction 11

Ingredients and supplements 12

Functional foods and drinks 13

Medical foods 14

Convergence of pharma, food & drinks in diabetes 14

Challenges and opportunities in the prevention and treatment of diabetes 16

Chapter 1 Introduction 17

Summary 17

Introduction 18

Diabetes, obesity and lifestyle changes 20

Diagnosis 23

Long term complications 24

Dietary impact 24

Prevention & treatment 28

Market opportunities 31

The Food Ingredients Sector 31

Fortified/functional foods 33

Dietary supplements 34

Medical foods 35

Pharmaceutical products 35

Report outline 37

Chapter 2 Ingredients and supplements 38

Summary 38

Introduction 39

Increasing insulin secretion & insulin sensitivity 41

Botanicals & Natural Product Extracts 42

Bitter melon 42

Gymnema sylvestre 44

Heartwood 45

Product case study: Diabecon (The Himalaya Drug Company) 46

Reducing oxidative stress 48

Minerals & Vitamins 49

Minerals 49

Vitamins 49

Phytonutrients 51

Cinnamon 51

Green tea 52

Reducing glucose absorption 53

Banaba 54

Fenugreek 54

Salvia hispanica 55

Soy protein 55

Reducing inflammation 56

Omega 3 56

Reducing sugar cravings & sugar intake 57

Rebiana 58

Conclusions 59

Chapter 3 Functional food and drinks 60

Summary 60

Introduction 61

Artificial & natural sweeteners 63

Functional food & drinks 66

New product developments 69

Functional foods 72

Fiber enriched foods 72

Case Study: General Mills 74

Fiber-like resistant starch 76

Case Study: Cargill 77

Non-digestible prebiotic fiber 78

Case Study: BENEO group 79

Sugar free & low calorie confectionery 81

Case study: Mars Inc 82

Conclusions on functional foods 83

Functional drinks 83

Nutritional supplement drinks & shakes 84

Fiber enriched drinks 84

Protein enriched drinks 85

Soft drinks 86

Carbonated drinks 86

Case study: PepsiCo 87

Products 87

Research & development 87

Fortified waters 88

Case study: CocaCola 89

Fortified & functional fruit juices 90

Hot drinks 91

Case study: Unilever 93

Research 94

Conclusions on functional drinks 94

Overall conclusions 95

Chapter 4 Medical foods 96

Summary 96

Introduction 97

Diabetes-specific formulas 98

Case Study: Abbott Nutrition 100

Case Study: Ajinomoto 104

Case Study: Groupe Danone 105

Case Study: Nestlé 108

Case Study: Kalbe Nutritionals 111

Case Study: Victus Inc 112

Conclusions 113

Chapter 5 Convergence of pharma, biotech, food and drinks 115

Summary 115

Introduction 116

New targets for weight management & diabetes 117

Case Study: EGCG 119

Case Study: Hoodia extract 119

Case study: WG0401 120

Case study: InterMed Discovery 120

New targets for diabetes 121

Case study: Madeglucyl 122

Case study: Resveratrol 123

New targets for diabetic complications 124

Emerging business models 124

R&D constraints 125

Science a major driver 126

Predictive health status biomarkers 127

Application of nutrigenomics 128

Personalization of nutrition 130

Clinical assessment of new ingredients & products with health benefits 132

Case Study: Medicus Research 133

Regulatory requirements for dietary & health benefit claims 135

Conclusions 137

Chapter 6 Challenges & opportunities in the prevention & treatment of

diabetes 139

Summary 139

Introduction 140

Challenges 140

Changing regulatory environment 140

Changing dietary guidelines 142

Consumer education 144

Rising costs of product development 146

Commercial application of nutrigenomics 147

Opportunities 147

The emerging consumer 147

Evolution of healthcare nutrition 150

Targeting diabetic complications & high risk consumers 151

Identification of functional ingredients & foods 152

Market trends 153

Overall Conclusions 154

Chapter 7 Appendix 155

Primary research methodology 155

Acknowledgments 155

Glossary 156

Bibliography 158



Table of figures

Figure 1: Nutrition and Medical Nutrition Therapy (MNT) 19

Figure 2: Prevalence (%) estimates of diabetes (20-79) by region, 2010 and 2030 20

Figure 3: Impact of low and high GI foods on Blood glucose 25

Figure 4: Traffic light for GI foods 26

Figure 5: Foods most likely to be avoided by consumers in 2008 and 2010 27

Figure 6: Ingredients, supplements and nutrients 28

Figure 7: Leading oral/injectable anti diabetic drugs 29

Figure 8: The health and nutrition sector 31

Figure 9: Key US consumer health concerns, 2007 32

Figure 10: The role of food and pharmaceuticals in the healthcare continuum 33

Figure 11: Hormonal control of blood glucose 42

Figure 12: Reduction in blood sugar levels in type 2 diabetic patients using Diabecon 48

Figure 13: Cinnamon products 52

Figure 14: Green Tea products 53

Figure 15: Fenugreek products 55

Figure 16: Traffic Light Labelling 62

Figure 17: New product developments targeting diabetes, 2005-2010* 71

Figure 18: Diabetic Lifestyle low glycemic fiber enriched bread for diabetics 73

Figure 19: U.S. General Mills Uncle Sam Low GI Cereal 74

Figure 20: Racconto Essentials resistant starch enriched pasta suitable for diabetics 77

Figure 21: Snugbury prebiotic fiber enriched diabetic ice cream 79

Figure 22: Fiber enriched GlucoBurst diabetic drink 85

Figure 23: Functional soft drinks suitable for diabetics 86

Figure 24: Fortified water suitable for diabetics 88

Figure 25: Dog On It! fortified juices targeting young diabetics 91

Figure 26: Different types of medical food and their uses 99

Figure 27: Abbotts leading medical foods 102

Figure 28: Danone’s Diasip 106

Figure 29: Nestlé Nutren range 109

Figure 30: Nestlé Boost Glucose Control 110

Figure 31: Kalbe Nutritionals’ Diabetasol 112

Figure 32: Victus’ Enterex range 113

Figure 33: Therapeutic targets for regulation of food intake 118

Figure 34: R&D investment of the food and drink industry around the world 126

Figure 35: Scientific and technological expertise driving health nutrition 131

Figure 36: Nestlés research and translational model: Diabetes 132

Figure 37: Medicus Research CRO services for Natural Product Development 134

Figure 38: Challenges and opportunities in the prevention of diabetes 140

Figure 39: Global population failing to achieve recommended intake 145

Figure 40: Factors influencing purchasing decisions 146

Figure 41: Emerging consumers 148

Figure 42: Emerging consumer segmentation 149

Figure 43: New business models driving healthcare nutrition 150

Figure 44: Diabetic complications 152



Table of tables

Table 1: Definitions of terms relating to diabetes 22

Table 2: Prevention and treatment strategies for diabetes 40

Table 3: Ingredient profile 47

Table 4: Natural & Artificial Sweeteners Approved in the US 64

Table 5: Natural & Artificial Sweeteners Approved in the US (continued) 65

Table 6: Superfruits 68

Table 7: Superfruits (continued) 69

Table 8: Functional herbal teas 92

Table 9: Medical foods and companies 101

Table 10: Drivers of pharma and food and drink products 125

Table 11: Strategic alliances and investments in R&D technologies 127

Table 12: Food choices for diabetes recommended by Nutrition Subcommittee of the Diabetes

Care Advisory Committee of Diabetes UK 143

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